Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas. Introduction: Juvenile nasopharyngeal angiofibroma (NAJ) is a tumor with .. Acessos Cirúrgicos no Angiofibroma Nasofaríngeo Juvenil – Relato de caso e. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the.

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Angiofibroma nasofaríngeo juvenil

Figure 7 shows mast cells in toluidine blue stain. This may be attributed to a rich vasculature and lack of encapsulation. Evaluation of the effectiveness of preoperative embolization in surgery for nasopharyngeal angiofibroma.

Endoscopic Ressection of Juvenile Angiofibroma: Loss of expression of GSTM 1 null genotype is seen in this tumor. The mean hospital stay of all patients was 12 days range, 3—39 days.

Over the years the access route for the treatment of NAJ has been modified with the aim of developing techniques with lower morbidity and lower incidence of recurrence. All these procedures lead to changes in the growth of the midface and craniofacial deformities even because of osteotomies performed during these procedures.

Nasopharyngeal angiofibroma – Wikipedia

For all other comments, please send your remarks via contact us. The color depends on the vascular component and may angiofinroma from pale white in less vascular lesions to a pink and wine colored mass in highly vascularized ones. Salvage Surgery in the Treatment of Local Recurrences of A total of 12 patients had undergone surgery 20 surgical interventions prior to being operated on at our service, performing a subtotal resection of the tumour, a biopsy of the tumour or a reduction of the tumour without achieving its total resection.


Click here for patient related inquiries. The major concern regarding the choice of angiofigroma is the rate of tumor recurrence, which has generated much discussion.

Mast cells and T-lymphocytes in juvenile angiofibromas. Previous article Next article. Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy; and specialized imaging techniques such as arteriography, CT, and magnetic resonance imaging MRI.

Endoscopic xngiofibroma alone or with other conventional techniques was safe for the treatment of angiofibromas of different stages.

Of our 20 patients, only 2 underwent surgery without embolization, with these 2 showing significantly greater intraoperative bleeding than the 18 patients who underwent embolization. Many studies highlight the benefit of preoperative arterial embolization to control bleeding intraoperative 16,29, However, as in any invasive procedure, embolization presents risks that should be fully explained to the patients Articles from Journal of Oral and Maxillofacial Pathology: Eur Arch Otorrhinolaryngol,pp.

The location and size of the tumor and feeding vessels are clearly demonstrated by this technique. How to cite this article. Braz J Otorhinolaryngol, 76pp.

Pathology Outlines – Nasopharyngeal angiofibroma

A higher density toward the periphery angiotibroma noted, which was seen in the present case too. Tumor size was not associated with bleeding. Laterally, these tumors may extend to and fill the pterygomaxillary fossa, causing the posterior wall of the maxillary sinus to bulge and eroding the pterygoid plate.

A wait and watch policy with periodic imaging may thus postpone or eliminate the need for surgery and reduce morbidity. One of the advantages of endoscopic approaches is less intraoperative blood loss, although this also depends on the availability and quality of embolisation, as well as tumour stage and location. Juvenile nasopharyngeal angiofibromas present almost exclusively in men aged years Click here for information on linking to our website or using our content or images.


Am J Clin Pathol.

Numerical sex chromosome aberrations in juvenile angiofibromas: Inter Journal of Pediatric Otorhinolaryngology. Examinations such as computed tomography, nuclear magnetic resonance and even nasal angiotibroma can clearly establish the extent of the tumor, its pattern of spread, and consequently, surgical planning 10,11,12,16,17,18, In 5 of them, we observed no radiological progression of the tumour or symptoms derived thereof during follow-up 78 months on average.

Sign up for our Email Newsletters. We also quantified mean blood loss during surgery and transfusion requirements. It impinges on adjacent structures and causes pressure erosion of bone.

Juvenile nasopharyngeal angiofibroma

These procedures were performed early in the surgery so we could anchor in parameters and well-known landmarks. Indian J Dent Res. Int J Pediatr Otorhinolaryngol.

Endoscopic Surgery in Treatment of Juvenile Nasopharyngeal angiofibroma. Over the angiofibromz 10 years the treatment of this disease has been discussed with the aim of designing a management protocol. A comparative study of surgical approches. Ann Otol Rhinol Laryngol.